Le pubblicazioni dei componenti di Est srl.
2024
Caccavo, Diego; Lamberti, Gaetano; Barba, Anna Angela
Analysis and simulation of wet-granulation processes Journal Article
In: Journal of the Taiwan Institute of Chemical Engineers, vol. 159, iss. 105455, 2024.
Abstract | Links | BibTeX | Tag: Dynamic image analysis, Modeling, Particle size distribution, Population balance equation, Wet-granulation
@article{Caccavo2024,
title = {Analysis and simulation of wet-granulation processes},
author = {Diego Caccavo and Gaetano Lamberti and Anna Angela Barba},
url = {https://doi.org/10.1016/j.jtice.2024.105455},
doi = {10.1016/j.jtice.2024.105455},
year = {2024},
date = {2024-03-22},
urldate = {2024-03-22},
journal = {Journal of the Taiwan Institute of Chemical Engineers},
volume = {159},
issue = {105455},
abstract = {Size enlargement by wet-granulation is one of the most important unit operation in several industrial fields: pharmaceutics, food processing, animal nutrition, agronomics, and so on. A lot of techniques have been used in order to measure the particle size distributions (PSD) and a few different approaches are available to model the PSD evolution during the process, mainly based on population balance equations (PBE). However, difficulties in both the activities (reliable measurement and robust modeling) have hindered their diffusion in industrial practice, keeping the granulation closer to an art than to a science.Size enlargement by wet-granulation is one of the most important unit operation in several industrial fields: pharmaceutics, food processing, animal nutrition, agronomics, and so on. A lot of techniques have been used in order to measure the particle size distributions (PSD) and a few different approaches are available to model the PSD evolution during the process, mainly based on population balance equations (PBE). However, difficulties in both the activities (reliable measurement and robust modeling) have hindered their diffusion in industrial practice, keeping the granulation closer to an art than to a science.},
keywords = {Dynamic image analysis, Modeling, Particle size distribution, Population balance equation, Wet-granulation},
pubstate = {published},
tppubtype = {article}
}
Size enlargement by wet-granulation is one of the most important unit operation in several industrial fields: pharmaceutics, food processing, animal nutrition, agronomics, and so on. A lot of techniques have been used in order to measure the particle size distributions (PSD) and a few different approaches are available to model the PSD evolution during the process, mainly based on population balance equations (PBE). However, difficulties in both the activities (reliable measurement and robust modeling) have hindered their diffusion in industrial practice, keeping the granulation closer to an art than to a science.Size enlargement by wet-granulation is one of the most important unit operation in several industrial fields: pharmaceutics, food processing, animal nutrition, agronomics, and so on. A lot of techniques have been used in order to measure the particle size distributions (PSD) and a few different approaches are available to model the PSD evolution during the process, mainly based on population balance equations (PBE). However, difficulties in both the activities (reliable measurement and robust modeling) have hindered their diffusion in industrial practice, keeping the granulation closer to an art than to a science.
2023
Apicella, Marco; Amato, Giuseppe; de Bartolomeis, Pietro; Barba, Anna Angela; De Feo, Vincenzo
Natural Food Resource Valorization by Microwave Technology: Purslane Stabilization by Dielectric Heating Journal Article
In: Foods , vol. 12, iss. 23, no 4247, 2023.
Abstract | Links | BibTeX | Tag: dielectric heating, fatty acids, food recovery, future food, microwave drying technology, phytosterols, Portulaca oleracea L., valorization
@article{Apicella2023,
title = {Natural Food Resource Valorization by Microwave Technology: Purslane Stabilization by Dielectric Heating},
author = {Marco Apicella and Giuseppe Amato and {de Bartolomeis, Pietro} and Anna Angela Barba and {De Feo, Vincenzo}},
url = { https://doi.org/10.3390/foods12234247},
doi = {10.3390/foods12234247},
year = {2023},
date = {2023-11-24},
urldate = {2023-11-24},
journal = {Foods },
volume = {12},
number = {4247},
issue = {23},
abstract = {The application of microwave-assisted drying is a promising technique due to the features of process sustainability that are usable for responsible productions. It is largely applied for the stabilization of food products, especially in the agro-food sector. In this study, the weed Portulaca oleracea L. (purslane), with its richness in antioxidant components in addition to its recognized pharmacological properties, has been considered due to its potential to be a natural, well-accepted future food. Attention was focused on the role of the heat and mass transfer rates involved in the drying processes on the nutritional profile of the dried products. For this purpose, different drying protocols (convective, microwave irradiation, microwave-vacuum irradiation) were applied to different parts of purslane herb (apical, twigs, entire structures) and chemical characterizations were performed by a GC/MS analysis of the extracts of the dried products. The results show that microwave treatments can assure a better preservation of fatty acids such as SFAs, MUFAs, and PUFAs (which constitute over 90% of the total components in the apical part, 65% in twigs, and 85% in microwave-vacuum-dried entire purslane samples) and phytosterols (their highest preservation was found in microwave-dried twigs) compared with convective treatments. The chemical composition variability as well as treatment times depend on the drying rates (in microwave treatments, the times are on a minute scale and the rates are up to three orders of magnitude greater than convective ones), which in turn depend on the heating transport phenomena. This variability can lead towards products that are diversified by properties that transform a weed into a valorized food source.},
keywords = {dielectric heating, fatty acids, food recovery, future food, microwave drying technology, phytosterols, Portulaca oleracea L., valorization},
pubstate = {published},
tppubtype = {article}
}
The application of microwave-assisted drying is a promising technique due to the features of process sustainability that are usable for responsible productions. It is largely applied for the stabilization of food products, especially in the agro-food sector. In this study, the weed Portulaca oleracea L. (purslane), with its richness in antioxidant components in addition to its recognized pharmacological properties, has been considered due to its potential to be a natural, well-accepted future food. Attention was focused on the role of the heat and mass transfer rates involved in the drying processes on the nutritional profile of the dried products. For this purpose, different drying protocols (convective, microwave irradiation, microwave-vacuum irradiation) were applied to different parts of purslane herb (apical, twigs, entire structures) and chemical characterizations were performed by a GC/MS analysis of the extracts of the dried products. The results show that microwave treatments can assure a better preservation of fatty acids such as SFAs, MUFAs, and PUFAs (which constitute over 90% of the total components in the apical part, 65% in twigs, and 85% in microwave-vacuum-dried entire purslane samples) and phytosterols (their highest preservation was found in microwave-dried twigs) compared with convective treatments. The chemical composition variability as well as treatment times depend on the drying rates (in microwave treatments, the times are on a minute scale and the rates are up to three orders of magnitude greater than convective ones), which in turn depend on the heating transport phenomena. This variability can lead towards products that are diversified by properties that transform a weed into a valorized food source.
Mancino, Raffaele; Caccavo, Diego; Barba, Anna Angela; Lamberti, Gaetano; Biasin, Alice; Cortesi, Angelo; Grassi, Gabriele; Grassi, Mario; Abrami, Michela
Agarose Cryogels: Production Process Modeling and Structural Characterization Journal Article
In: Gels, vol. 9, iss. 9, no 765, 2023, ISSN: 23102861.
Abstract | Links | BibTeX | Tag: agarose, cryogels, Equilibrium, Hydrogels, Modeling, rheology
@article{Mancino2023,
title = {Agarose Cryogels: Production Process Modeling and Structural Characterization },
author = {Raffaele Mancino and Diego Caccavo and Anna Angela Barba and Gaetano Lamberti and Alice Biasin and Angelo Cortesi and Gabriele Grassi and Mario Grassi and Michela Abrami},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85172281028&doi=10.3390%2fgels9090765&partnerID=40&md5=7753d30977c1b97694c4ede138749d57},
doi = {10.3390/gels9090765},
issn = {23102861},
year = {2023},
date = {2023-09-20},
urldate = {2023-09-20},
journal = {Gels},
volume = {9},
number = {765},
issue = {9},
abstract = {A cryogel is a cross-linked polymer network with different properties that are determined by its manufacturing technique. The formation of a cryogel occurs at low temperatures and results in a porous structure whose pore size is affected by thermal conditions. The adjustable pore sizes of cryogels make them attractive for diverse applications. In this study, the influence of the external operational temperature, which affects the cooling and freezing rates, on the production of cryogels with 2% w/w agarose is investigated. Moreover, a mathematical model is developed to simulate the cryogel production process and provide an initial estimate of the pore size within the structure. The predictions of the model, supported by qualitative light microscopy images, demonstrate that cryogels produced at higher process temperatures exhibit larger pore sizes. Moreover, the existence of pore size distribution within the gel structure is confirmed. Finally, stress relaxation tests, coupled with an image analysis, validates that cryogels produced at lower temperatures possess a higher stiffness and slower water release rates.},
keywords = {agarose, cryogels, Equilibrium, Hydrogels, Modeling, rheology},
pubstate = {published},
tppubtype = {article}
}
A cryogel is a cross-linked polymer network with different properties that are determined by its manufacturing technique. The formation of a cryogel occurs at low temperatures and results in a porous structure whose pore size is affected by thermal conditions. The adjustable pore sizes of cryogels make them attractive for diverse applications. In this study, the influence of the external operational temperature, which affects the cooling and freezing rates, on the production of cryogels with 2% w/w agarose is investigated. Moreover, a mathematical model is developed to simulate the cryogel production process and provide an initial estimate of the pore size within the structure. The predictions of the model, supported by qualitative light microscopy images, demonstrate that cryogels produced at higher process temperatures exhibit larger pore sizes. Moreover, the existence of pore size distribution within the gel structure is confirmed. Finally, stress relaxation tests, coupled with an image analysis, validates that cryogels produced at lower temperatures possess a higher stiffness and slower water release rates.
De Piano, Raffaella; Caccavo, Diego; Barba, Anna Angela; Lamberti, Gaetano
Polyelectrolyte hydrogels in biological systems: Modeling of swelling and deswelling behavior Journal Article
In: Chemical Engineering Science, vol. 279, 2023.
Abstract | Links | BibTeX | Tag: Equilibrium, Hydrogels, Modeling, nutraceuticals, Polyelectrolytes
@article{nokey,
title = {Polyelectrolyte hydrogels in biological systems: Modeling of swelling and deswelling behavior},
author = {{De Piano, Raffaella} and Diego Caccavo and Anna Angela Barba and Gaetano Lamberti},
doi = {https://doi.org/10.1016/j.ces.2023.118959},
year = {2023},
date = {2023-06-05},
urldate = {2023-06-05},
journal = {Chemical Engineering Science},
volume = {279},
abstract = {Polyelectrolyte hydrogels are a particular class of hydrogel whose behavior is connected to the variation of pH in the surrounding solution. Their behavior is influenced by the ionizable groups present on their chain. These groups could be acid or basic and polyelectrolytes could be anionic or cationic. To fully understand their behavior mathematical modeling has been widely used over many years. In this work a model based on a monophasic approach will be used to describe a general behavior of anionic hydrogels in a steady state condition at pH lower (or equal) to seven. Free swelling experiments and constrained swelling experiments have been simulated varying the parameters of the model to highlight the properties of the material. From a comparison with experimental data, it results that the proposed model can describe the general behavior of the system as described in the literature.},
keywords = {Equilibrium, Hydrogels, Modeling, nutraceuticals, Polyelectrolytes},
pubstate = {published},
tppubtype = {article}
}
Polyelectrolyte hydrogels are a particular class of hydrogel whose behavior is connected to the variation of pH in the surrounding solution. Their behavior is influenced by the ionizable groups present on their chain. These groups could be acid or basic and polyelectrolytes could be anionic or cationic. To fully understand their behavior mathematical modeling has been widely used over many years. In this work a model based on a monophasic approach will be used to describe a general behavior of anionic hydrogels in a steady state condition at pH lower (or equal) to seven. Free swelling experiments and constrained swelling experiments have been simulated varying the parameters of the model to highlight the properties of the material. From a comparison with experimental data, it results that the proposed model can describe the general behavior of the system as described in the literature.
Piano, Raffaelle De; Caccavo, Diego; Lamberti, Gaetano; Remaut, Katrien; Seynaeve, Hanne; Barba, Anna Angela
A New Productive Approach and Formulative Optimization for Curcumin Nanoliposomal Delivery Systems Journal Article
In: Pharmaceutics, vol. 15, iss. 3, no 959, 2023, ISSN: 19994923.
Abstract | Links | BibTeX | Tag: anticancer, antioxidant activity, curcumin, nanoliposomes, nanotechnologies, nutraceuticals, simil-microfluidic technology
@article{Piano}2023,
title = {A New Productive Approach and Formulative Optimization for Curcumin Nanoliposomal Delivery Systems},
author = {Raffaelle {De Piano} and Diego Caccavo and Gaetano Lamberti and Katrien Remaut and Hanne Seynaeve and Anna Angela Barba},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85151381874&doi=10.3390%2fpharmaceutics15030959&partnerID=40&md5=fceef78253390aceb67f23b8ff583eb8},
doi = {10.3390/pharmaceutics15030959},
issn = {19994923},
year = {2023},
date = {2023-03-16},
urldate = {2023-03-16},
journal = {Pharmaceutics},
volume = {15},
number = {959},
issue = {3},
abstract = {The use of natural resources and the enhancing of technologies are outlining the strategies of modern scientific-technological research for sustainable health products manufacturing. In this context, the novel simil-microfluidic technology, a mild production methodology, is exploited to produce liposomal curcumin as potential powerful dosage system for cancer therapies and for nutraceutical purposes. Through simil-microfluidic technology, based on interdiffusion phenomena of a lipid-ethanol phase in an aqueous flow, massive productions of liposomes at nanometric scale can be obtained. In this work, studies on liposomal production with useful curcumin loads were performed. In particular, process issues (curcumin aggregations) were elucidated and formulation optimization for curcumin load was performed. The main achieved result has been the definition of operative conditions for nanoliposomal curcumin production with interesting loads and encapsulation efficiencies.},
keywords = {anticancer, antioxidant activity, curcumin, nanoliposomes, nanotechnologies, nutraceuticals, simil-microfluidic technology},
pubstate = {published},
tppubtype = {article}
}
The use of natural resources and the enhancing of technologies are outlining the strategies of modern scientific-technological research for sustainable health products manufacturing. In this context, the novel simil-microfluidic technology, a mild production methodology, is exploited to produce liposomal curcumin as potential powerful dosage system for cancer therapies and for nutraceutical purposes. Through simil-microfluidic technology, based on interdiffusion phenomena of a lipid-ethanol phase in an aqueous flow, massive productions of liposomes at nanometric scale can be obtained. In this work, studies on liposomal production with useful curcumin loads were performed. In particular, process issues (curcumin aggregations) were elucidated and formulation optimization for curcumin load was performed. The main achieved result has been the definition of operative conditions for nanoliposomal curcumin production with interesting loads and encapsulation efficiencies.
2022
Barba, Anna Angela; Lamberti, Gaetano; Caccavo, Diego
Special Issue: Enhancement for Strategies in Liposomal and Niosomal Preparations: Formulative and Technological Innovations Journal Article
In: Pharmaceutics, 2022.
Abstract | Links | BibTeX | Tag: coating, drug delivery systems, drug encapsulation, formulation development, lipid vesicles, liposomes, nano/microcarriers, niosomes, process intensification, sustainable processes
@article{Barba2022,
title = {Special Issue: Enhancement for Strategies in Liposomal and Niosomal Preparations: Formulative and Technological Innovations},
author = {Anna Angela Barba and Gaetano Lamberti and Diego Caccavo },
url = {https://www.mdpi.com/journal/pharmaceutics/special_issues/liposomal_niosomal
http://est.srl/wp-content/uploads/2022/05/Enhancement-for-Strategies-in-Liposomal-and-Niosomal.pdf},
year = {2022},
date = {2022-05-12},
urldate = {2022-05-12},
journal = { Pharmaceutics},
abstract = {Currently, industrial pharmaceutical/nutraceutical manufacturing has to comply with two major needs: the mandatory regulations for formulation safety and the sustainability of production. Within this framework, the role of scientific research into more powerful drug delivery systems appears to be highly relevant because it can give responses to the industry about both the formulative and preparative issues.
Lipid-based drug delivery systems are recognized as safe and effective carriers. The different classes of liposomal and niosomal vesicles are the main expression of delivery systems for which formulation and preparation can be easily tailored to meet different disease conditions, routes of administration, structures (coated, functionalized, stealth) and size s(micro-nano), stabilities, and costs.
This Special Issue aims to collect cutting-edge research results on liposomes and niosomes that have been achieved through both formulative and preparative new approaches, with the aim of moving towards advanced technologies for pharmaceutical manufacturing. A key point of this Special Issue is to connect multidisciplinary competences in drug membrane-mimetic delivery systems.
We are pleased to invite you to share your results contributing to how we can resolve the above-introduced pharmaceutic production needs. In this Special Issue, original research articles and reviews are welcome.},
keywords = {coating, drug delivery systems, drug encapsulation, formulation development, lipid vesicles, liposomes, nano/microcarriers, niosomes, process intensification, sustainable processes},
pubstate = {published},
tppubtype = {article}
}
Currently, industrial pharmaceutical/nutraceutical manufacturing has to comply with two major needs: the mandatory regulations for formulation safety and the sustainability of production. Within this framework, the role of scientific research into more powerful drug delivery systems appears to be highly relevant because it can give responses to the industry about both the formulative and preparative issues.
Lipid-based drug delivery systems are recognized as safe and effective carriers. The different classes of liposomal and niosomal vesicles are the main expression of delivery systems for which formulation and preparation can be easily tailored to meet different disease conditions, routes of administration, structures (coated, functionalized, stealth) and size s(micro-nano), stabilities, and costs.
This Special Issue aims to collect cutting-edge research results on liposomes and niosomes that have been achieved through both formulative and preparative new approaches, with the aim of moving towards advanced technologies for pharmaceutical manufacturing. A key point of this Special Issue is to connect multidisciplinary competences in drug membrane-mimetic delivery systems.
We are pleased to invite you to share your results contributing to how we can resolve the above-introduced pharmaceutic production needs. In this Special Issue, original research articles and reviews are welcome.
Lipid-based drug delivery systems are recognized as safe and effective carriers. The different classes of liposomal and niosomal vesicles are the main expression of delivery systems for which formulation and preparation can be easily tailored to meet different disease conditions, routes of administration, structures (coated, functionalized, stealth) and size s(micro-nano), stabilities, and costs.
This Special Issue aims to collect cutting-edge research results on liposomes and niosomes that have been achieved through both formulative and preparative new approaches, with the aim of moving towards advanced technologies for pharmaceutical manufacturing. A key point of this Special Issue is to connect multidisciplinary competences in drug membrane-mimetic delivery systems.
We are pleased to invite you to share your results contributing to how we can resolve the above-introduced pharmaceutic production needs. In this Special Issue, original research articles and reviews are welcome.
De Martino, Laura; Caputo, Lucia; Amato, Giuseppe; Iannone, Marco; Barba, Anna Angela; De Feo, Vincenzo
Postharvest Microwave Drying of Basil (Ocimum basilicum L.): The Influence of Treatments on the Quality of Dried Products Journal Article
In: Foods, vol. 11, no 1029, pp. 11, 2022.
Abstract | Links | BibTeX | Tag: drying methods, essential oil, microwave heating, Ocimum basilicum L., process sustainability
@article{Martino2022,
title = {Postharvest Microwave Drying of Basil (Ocimum basilicum L.): The Influence of Treatments on the Quality of Dried Products},
author = { {De Martino, Laura} and Lucia Caputo and Giuseppe Amato and Marco Iannone and Anna Angela Barba and {De Feo, Vincenzo}},
editor = {MDPI},
url = {http://est.srl/de-martino-et-al-2022-foods-11-1029-1042/},
doi = {https://doi.org/10.3390/foods11071029},
year = {2022},
date = {2022-04-01},
urldate = {2022-04-01},
journal = {Foods},
volume = {11},
number = {1029},
pages = {11},
abstract = {Edible herbs are widely used in the human diet due to their pleasant flavors and countless health benefits associated with their components having, mainly, antioxidant and anti-inflammatory therapeutic functions. Since herbs are highly perishable materials because of their high water content, to guarantee products are safe and stable over time, it is necessary that they undergo stabilization operations. The application of microwave-assisted drying, a promising technique in terms of process sustainability, for the stabilization of the aromatic herb, Ocimum basilicum L., was investigated. The activities were carried out by applying different operating conditions in order to evaluate the impact of the time/temperature combination on the final quality of dried basil. The latter was investigated via the chemical characterization of extracted essential oils and tissue damages. Conventional convective processes were also applied to perform comparisons between dried basil products both under production and the quality preservation points of view. Results showed that microwave heating is suitable as a drying method, as expected, due to the well-known interaction between vegetable tissue (rich in water) and the electromagnetic field; and that drying methods have a different influence on the chemical composition of the essential oils extracted from dried products, in terms of the number (ranging from 41 to 18 components in different dried samples) and percentage (until 67% in linalool and 21% in α-trans-bergamotene in different dried samples) of its’ constituents.},
keywords = {drying methods, essential oil, microwave heating, Ocimum basilicum L., process sustainability},
pubstate = {published},
tppubtype = {article}
}
Edible herbs are widely used in the human diet due to their pleasant flavors and countless health benefits associated with their components having, mainly, antioxidant and anti-inflammatory therapeutic functions. Since herbs are highly perishable materials because of their high water content, to guarantee products are safe and stable over time, it is necessary that they undergo stabilization operations. The application of microwave-assisted drying, a promising technique in terms of process sustainability, for the stabilization of the aromatic herb, Ocimum basilicum L., was investigated. The activities were carried out by applying different operating conditions in order to evaluate the impact of the time/temperature combination on the final quality of dried basil. The latter was investigated via the chemical characterization of extracted essential oils and tissue damages. Conventional convective processes were also applied to perform comparisons between dried basil products both under production and the quality preservation points of view. Results showed that microwave heating is suitable as a drying method, as expected, due to the well-known interaction between vegetable tissue (rich in water) and the electromagnetic field; and that drying methods have a different influence on the chemical composition of the essential oils extracted from dried products, in terms of the number (ranging from 41 to 18 components in different dried samples) and percentage (until 67% in linalool and 21% in α-trans-bergamotene in different dried samples) of its’ constituents.
Iannone, Marco; Caccavo, Diego; Lamberti, Gaetano; Barba, Anna Angela
A low-cost push–pull syringe pump for continuous flow applications Journal Article
In: HardwareX, vol. 11, 2022.
Abstract | Links | BibTeX | Tag: 3D-printing, Continuous flow, Dual syringe pump, Prova, Push–pull
@article{Iannone2022,
title = {A low-cost push–pull syringe pump for continuous flow applications},
author = {Marco Iannone and Diego Caccavo and Gaetano Lamberti and Anna Angela Barba},
editor = {Elsevier},
url = {http://est.srl/iannone-et-al-hardwarex-volume-11-april-2022-e00295-2/},
doi = {https://doi.org/10.1016/j.ohx.2022.e00295},
year = {2022},
date = {2022-03-16},
urldate = {2022-03-16},
journal = {HardwareX},
volume = {11},
abstract = {Syringe pumps are very useful tools to ensure a constant and pulsation-free flow rate, how-ever usability is limited to batch processes. This article shows an open-source method for manufacturing a push pull syringe pump, valid for continuous processes, easy to build, low-cost and programmable.
The push–pull syringe pump (PPSP) is driven by an Arduino nano ATmega328P which controls a NEMA 17 in microstepping via the A4988 stepper driver. The Push-Pull Syringe Pump setup is configurable by means of a digital encoder and an oled screen programmed using C ++. A PCB was designed and built to facilitate the assembly of the device. The continuous flow is guaranteed by four non-return valves and a dampener, which has been sized and optimized for use on this device. Finally, tests were carried out to evaluate the flow rates and the linearity of the flow. The device is achievable with a cost of less than 100 €.},
keywords = {3D-printing, Continuous flow, Dual syringe pump, Prova, Push–pull},
pubstate = {published},
tppubtype = {article}
}
Syringe pumps are very useful tools to ensure a constant and pulsation-free flow rate, how-ever usability is limited to batch processes. This article shows an open-source method for manufacturing a push pull syringe pump, valid for continuous processes, easy to build, low-cost and programmable.
The push–pull syringe pump (PPSP) is driven by an Arduino nano ATmega328P which controls a NEMA 17 in microstepping via the A4988 stepper driver. The Push-Pull Syringe Pump setup is configurable by means of a digital encoder and an oled screen programmed using C ++. A PCB was designed and built to facilitate the assembly of the device. The continuous flow is guaranteed by four non-return valves and a dampener, which has been sized and optimized for use on this device. Finally, tests were carried out to evaluate the flow rates and the linearity of the flow. The device is achievable with a cost of less than 100 €.
The push–pull syringe pump (PPSP) is driven by an Arduino nano ATmega328P which controls a NEMA 17 in microstepping via the A4988 stepper driver. The Push-Pull Syringe Pump setup is configurable by means of a digital encoder and an oled screen programmed using C ++. A PCB was designed and built to facilitate the assembly of the device. The continuous flow is guaranteed by four non-return valves and a dampener, which has been sized and optimized for use on this device. Finally, tests were carried out to evaluate the flow rates and the linearity of the flow. The device is achievable with a cost of less than 100 €.
Cuoco, Alessia; Iannone, Marco; Cavallo, Rosario; d'Amore, Matteo; Barba, Anna Angela
Grani Antichi: il rilancio della biodiversità Journal Article
In: Tecnologie Alimentari, vol. 2, pp. pp. 48 - 54, 2022.
Abstract | Links | BibTeX | Tag:
@article{Cuoco2022b,
title = {Grani Antichi: il rilancio della biodiversità},
author = {Alessia Cuoco and Marco Iannone and Rosario Cavallo and Matteo d'Amore and Anna Angela Barba},
url = {https://interprogettied.com/tecnologiealimentari/2022/04/tecnologie-alimentari-n2-marzo-aprile-2022/
http://est.srl/wp-content/uploads/2022/05/48_54_TE-n.-2-Grani-antichi-parte-2.pdf},
year = {2022},
date = {2022-03-01},
urldate = {2022-03-01},
journal = {Tecnologie Alimentari},
volume = {2},
pages = {pp. 48 - 54},
abstract = {Il rinnovato interesse verso la coltivazione di grani antichi è motivato da fattori socio-culturali, nonché dagli accertati benefici nutrizionali e salutistici dei prodotti di trasformazione. La ricerca scientifica promuove il rilancio della biodiversità di tali coltivazioni cerealicole, proponendo strategie innovative e sostenibili per la stabilizzazione post-raccolta dei frumenti antichi, considerati un patrimonio alimentare unico.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Il rinnovato interesse verso la coltivazione di grani antichi è motivato da fattori socio-culturali, nonché dagli accertati benefici nutrizionali e salutistici dei prodotti di trasformazione. La ricerca scientifica promuove il rilancio della biodiversità di tali coltivazioni cerealicole, proponendo strategie innovative e sostenibili per la stabilizzazione post-raccolta dei frumenti antichi, considerati un patrimonio alimentare unico.
Lamberti, Gaetano; Barba, Anna Angela
Produzione sostenibile: le nuove strategie sintetiche premiate dal Nobel Journal Article
In: ICF rivista dell’industria chimica e farmaceutica, 2022.
Abstract | Links | BibTeX | Tag: Sostenibilità
@article{Lamberti2022,
title = {Produzione sostenibile: le nuove strategie sintetiche premiate dal Nobel},
author = {Gaetano Lamberti and Anna Angela Barba },
url = {http://est.srl/icf-febb-22-produzione-sostenibile-premio-nobel-chimica-21articolo-barba/
https://interprogettied.com/icf/2022/04/11/icf-rivista-dellindustria-chimica-e-farmaceutica-n1-febbraio-marzo-2022/},
year = {2022},
date = {2022-02-01},
urldate = {2022-02-01},
journal = {ICF rivista dell’industria chimica e farmaceutica},
abstract = {L’assegnazione di un Nobel può essere un indicatore del grande impatto che una ricerca può avere nella vita di tutti. Nel 2021 è stato premiato
per la Chimica un nuovo approccio preparativo rivoluzionario per tanti settori produttivi, ma soprattutto per quello chimico-farmaceutico, basato
sull’organocatalisi asimmetrica.},
keywords = {Sostenibilità},
pubstate = {published},
tppubtype = {article}
}
L’assegnazione di un Nobel può essere un indicatore del grande impatto che una ricerca può avere nella vita di tutti. Nel 2021 è stato premiato
per la Chimica un nuovo approccio preparativo rivoluzionario per tanti settori produttivi, ma soprattutto per quello chimico-farmaceutico, basato
sull’organocatalisi asimmetrica.
per la Chimica un nuovo approccio preparativo rivoluzionario per tanti settori produttivi, ma soprattutto per quello chimico-farmaceutico, basato
sull’organocatalisi asimmetrica.
Cuoco, Alessia; Iannone, Marco; Cavallo, Rosario; d'Amore, Matteo; Barba, Anna Angela
Grani antichi: la diffusione delle coltivazioni e il mercato in Italia Journal Article
In: Tecnologie Alimentari, vol. 1, 2022.
Abstract | Links | BibTeX | Tag: Ambiente, Grani antichi, Ricerca di mercato, Sostenibilità
@article{Cuoco2022,
title = {Grani antichi: la diffusione delle coltivazioni e il mercato in Italia},
author = {Alessia Cuoco and Marco Iannone and Rosario Cavallo and Matteo d'Amore and Anna Angela Barba},
url = {http://est.srl/ta-n-1-2022-grani-antichi-1-2/
https://interprogettied.com/tecnologiealimentari/2022/02/tecnologie-alimentari-n1-gennaio-febbraio-2022/},
year = {2022},
date = {2022-01-03},
urldate = {2022-01-03},
journal = {Tecnologie Alimentari},
volume = {1},
abstract = {Cresce la rilevanza socio-economica dei grani antichi, non solo per l’interesse verso i “vecchi sapori”, ma anche per i loro benefici nutrizionali e salutistici, come confermano i dati di mercato. Non meno importanti sono la biodiversità e la sostenibilità legate al loro ciclo di coltura. In questo articolo sono presentate note sulla diffusione della coltivazione dei grani antichi in Italia e sulla crescente importanza in seno al mercato generale dei grani.},
keywords = {Ambiente, Grani antichi, Ricerca di mercato, Sostenibilità},
pubstate = {published},
tppubtype = {article}
}
Cresce la rilevanza socio-economica dei grani antichi, non solo per l’interesse verso i “vecchi sapori”, ma anche per i loro benefici nutrizionali e salutistici, come confermano i dati di mercato. Non meno importanti sono la biodiversità e la sostenibilità legate al loro ciclo di coltura. In questo articolo sono presentate note sulla diffusione della coltivazione dei grani antichi in Italia e sulla crescente importanza in seno al mercato generale dei grani.